Minimal Introns Are Not "Junk"
نویسندگان
چکیده
منابع مشابه
Mammalian Introns: When the Junk Generates Molecular Diversity
Introns represent almost half of the human genome, yet their vast majority is eliminated from eukaryotic transcripts through RNA splicing. Nevertheless, they feature key elements and functions that deserve further interest. At the level of DNA, introns are genomic segments that can shelter independent transcription units for coding and non-coding RNAs which transcription may interfere with that...
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BACKGROUND We previously have studied the insertion and deletion polymorphism by sequencing no more than one hundred introns in a mixed human population and found that the minimal introns tended to maintain length at an optimal size. Here we analyzed re-sequenced 179 individual genomes (from African, European, and Asian populations) from the data released by the 1000 Genome Project to study the...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2002
ISSN: 1088-9051
DOI: 10.1101/gr.224602